Trial Readiness Project

In preparation for large multi-center clinical trials, a study team including the University of Chicago, University of New Mexico, Mayo Clinic, Barrow Neurological Institute, University of California San Francisco, and the University of Utah, aimed to establish a research infrastructure for future trials.

Join the Patient Registry

Join patients around the world in building the Registry community.

More

The Trial Readiness project assessed potential patient cohorts across study sites and hemorrhage rates in those patient groups. The team validated the reproducibility and reliability of imaging biomarkers at multiple institutions. Study participants were asked to provide baseline clinical information with a group that was followed annually for two to three years.

For more information, view this informative WEBINAR delivered by Dr. Issam Awad.

Publications resulting from this study:

Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part I: Event Rates and Clinical Outcome

Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling

Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project

Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH)

 

Reviewed 4.10.25

Also In This Section